Memory consolidation refers to the process of stabilizing the trace of a memory after it is acquired. This process is made up of two distinct sub-processes, namely, synaptic consolidation and system consolidation.
In recent years, researchers have found that a third sub-process may contribute to the consolidation of memory, and this is called reconsolidation. Memory consolidation is an important mental function, because it enables human beings and animals to form and store memories.
Synaptic consolidation is the initial stage of memory consolidation. It can occur minutes after the brain has encountered and interacted with something. About six hours after learning, memories will become impervious to factors that can interfere with synaptic consolidation, and this will lead to the development of long-term memory.
The strength of synaptic consolidation is dependent on the efficiency of protein synthesis, the presence of dietary flavanoids, and other factors.
System consolidation happens after synaptic consolidation, and it is the process of reorganizing memories from the hippocampus to the neo-cortex, where they will be stored more permanently. In human beings, it can take as long as one or two decades for the process of system consolidation to be completed.
One essential part of system consolidation is rapid eye movement, or REM, which enables learning to occur in the brain’s hippocampal and cortical regions overnight. REM promotes neuronal plasticity after an enriched waking experience, and it plays an important role in the consolidation of memories.
Reconsolidation refers to the recalling and active consolidation of memories. Through this process, long-term memories are maintained, strengthened, and modified. After memories are consolidated, they are mostly considered stable, but a labile phase may occur when a memory trace is retrieved. Reconsolidation functions to stabilize memories after they are completely retrieved.